if you give a mouse a liver…

How does one develop treatments for cancer that has spread to the liver? for cancer that started in the liver, like Hepatoblastoma?  The first step in answering this question was a trial to convert a mouse liver to a human liver, so that human tumor cells would find it more inviting.  Is that what it took? Read Rishi’s online-first article here.     This work was in collaboration with the company Yecuris in Oregon (collaborator Lisa Wilson), the company Xentech in France (collaborative lead Stefano Cairo) and pathologist Atiya Mansoor at OHSU.  This project was funded by the Macy Easom Foundation.